CONNECTING DOTS IN DISORDERS OF GUT-BRAIN INTERACTION: THE INTERPLAY OF STRESS AND SEX HORMONES IN SHAPING VISCERAL PAIN

Connecting dots in disorders of gut-brain interaction: the interplay of stress and sex hormones in shaping visceral pain

Visceral pain and stress are tightly intertwined bodily and emotional phenomena, which enable a flexible adaptation to environmental challenges by activating a response repertoire to restore homeostasis along the gut-brain axis.However, visceral pain and stress can persist widely independent of the initial cause, acquiring independent disease value

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Upregulation of Glutamate Transporter 1 by Clavulanic Acid Administration and Attenuation of Allodynia and Hyperalgesia in Neuropathic Rats

Introduction: Clavulanic acid (CLAV) is structurally similar to ceftriaxone, a potent stimulator of glial GlutamateTransporter-1 (GLT-1) expression.The present study aims at exploring the anti-nociceptive effects of CLAV, a beta-lactamase inhibitor in rats underwent sciatic nerve Chronic Constriction Injury (CCI).Methods: CLAV (12.5, 25, 50 mg/kg)

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Evaluating the treatment of synthetic secondary treated tannery effluent by forward osmosis: Effect of draw solution concentration

Forward Osmosis (FO) is a suitable pretreatment process to Reverse Osmosis (RO) for secondary treated sewage reuse and secondary treated industrial effluents.In this study, FO process employing aquaporin FO membrane is investigated for concentrating synthetic secondary treated tannery effluents using 20 g/L and Party Games 38 g/L of NaCl solution a

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